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6-Biopterin

CAS No. 22150-76-1

6-Biopterin( L-Biopterin )

Catalog No. M20939 CAS No. 22150-76-1

6-Biopterin is a natural productis a NO synthase cofactor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    6-Biopterin
  • Note
    Research use only, not for human use.
  • Brief Description
    6-Biopterin is a natural productis a NO synthase cofactor.
  • Description
    6-Biopterin is a natural productis a NO synthase cofactor.
  • In Vitro
    6-biopterin is extremely cytotoxic to human melanocytes under in vitro conditions. Thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione. (6R)5,6,7,8 tetrahydrobiopterin undergoes redox-cycling by its oxidation to quinonoid dihydrobiopterin and to 6-biopterin through consecutive two electron oxidation reactions.
  • In Vivo
    ——
  • Synonyms
    L-Biopterin
  • Pathway
    NF-κB
  • Target
    NOD
  • Recptor
    NO synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    22150-76-1
  • Formula Weight
    237.22
  • Molecular Formula
    C9H11N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:6 mg/mL (25.29 mM)
  • SMILES
    C[C@H](O)[C@H](O)c1cnc2[nH]c(N)nc(=O)c2n1
  • Chemical Name
    2-amino-6-((1S2R)-12-dihydroxypropyl)pteridin-4(1H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Schallreuter K U Buttner G Pittelkow M R et al. Cytotoxicity of 6-Biopterin to Human Melanocytes[J]. Biochemical & Biophysical Research Communications 1994 204(1):0-48.
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