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Home - Products - Metabolic Enzyme/Protease - Phosphatase - SHP099

SHP099

CAS No. 1801747-42-1

SHP099( SHP099 free base | SHP099 | SHP-099 | SHP 099 )

Catalog No. M28048 CAS No. 1801747-42-1

SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SHP099
  • Note
    Research use only, not for human use.
  • Brief Description
    SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
  • Description
    SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SHP099 free base | SHP099 | SHP-099 | SHP 099
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1801747-42-1
  • Formula Weight
    352.26
  • Molecular Formula
    C16H19Cl2N5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 12 mg/mL (34.07 mM)
  • SMILES
    CC1(N)CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Smith JL, et al. Fusarium graminearum Mycotoxins in Maize Associated With Striacosta albicosta (Lepidoptera: Noctuidae) Injury. J Econ Entomol. 2018 Mar 14.
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