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Roseoflavin

CAS No. 51093-55-1

Roseoflavin( 8-Dimethylaminoriboflavin )

Catalog No. M14760 CAS No. 51093-55-1

Roseoflavin is a chemical analog of FMN and riboflavin that has antimicrobial activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Roseoflavin
  • Note
    Research use only, not for human use.
  • Brief Description
    Roseoflavin is a chemical analog of FMN and riboflavin that has antimicrobial activity.
  • Description
    Roseoflavin is a chemical analog of FMN and riboflavin that has antimicrobial activity; directly bind to FMN riboswitch aptamers (Kd=100 nM) and downregulate the expression of an FMN riboswitch-lacZ reporter gene in B. subtilis.
  • In Vitro
    Roseoflavin, a chemical analog of flavin mononucleotide (FMN) and riboflavin that has antimicrobial activity, can directly bind to FMN riboswitch (Kd~100 nM) aptamers and downregulate the expression of an FMN riboswitch-lacZ reporter gene in B. subtilis.
  • In Vivo
    ——
  • Synonyms
    8-Dimethylaminoriboflavin
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    51093-55-1
  • Formula Weight
    405.4
  • Molecular Formula
    C18H23N5O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (123.33 mM)
  • SMILES
    O=C(N1)N=C2N(C[C@H](O)[C@H](O)[C@H](O)CO)C3=CC(N(C)C)=C(C)C=C3N=C2C1=O
  • Chemical Name
    8-(dimethylamino)-7-methyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lee ER, et al. RNA Biol. 2009 Apr-Jun;6(2):187-94. 2. Wang H, et al. Cell Chem Biol. 2017 May 18;24(5):576-588.e6. 3. Langer S, et al. J Bacteriol. 2013 Sep;195(18):4037-45.
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