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Rbin-2

CAS No. 2032282-97-4

Rbin-2( —— )

Catalog No. M34391 CAS No. 2032282-97-4

Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Rbin-2
  • Note
    Research use only, not for human use.
  • Brief Description
    Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).
  • Description
    Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerfulprobe for the eukaryotic ribosome assembly.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Phosphatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2032282-97-4
  • Formula Weight
    335.22
  • Molecular Formula
    C13H11BrN4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 8.33 mg/mL (24.85 mM; Ultrasonic (<60°C)
  • SMILES
    S(CC(C)=C)C=1N=C2C(C=3C(N2)=CC(Br)=CC3)=NN1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kawashima SA, et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell. 2016 Oct 6;167(2):512-524.e14. ?
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