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RO8191
CAS No. 691868-88-9
RO8191( CDM-3008 | RO4948191 )
Catalog No. M27515 CAS No. 691868-88-9
RO8191 (CDM-3008), an imidazonaphthyridine compound, is an agonist of interferon (IFN) receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 48 | Get Quote |
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| 5MG | 80 | Get Quote |
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| 10MG | 132 | Get Quote |
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| 25MG | 290 | Get Quote |
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| 50MG | 462 | Get Quote |
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| 100MG | 672 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRO8191
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NoteResearch use only, not for human use.
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Brief DescriptionRO8191 (CDM-3008), an imidazonaphthyridine compound, is an agonist of interferon (IFN) receptor.
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DescriptionRO8191 (CDM-3008), an imidazonaphthyridine compound, is an agonist of interferon (IFN) receptor.(In Vitro):RO8191 strongly suppresses HCV replicon activity at 72 h in a dose-dependent manner. RO8191 reduces levels of the proteins HCV NS3 and NS4A, which are localized mainly in the perinuclear region of the replicon cells.(In Vivo):RO8191 significantly induces antiviral genes Oas1b, Mx1, and Pkr in the livers of six-week-old C57BL/6J mice.
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In Vitro——
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In Vivo——
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SynonymsCDM-3008 | RO4948191
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PathwayMicrobiology/Virology
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TargetHCV
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Recptorthyrotropin receptor (TSHR)
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Research Area——
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Indication——
Chemical Information
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CAS Number691868-88-9
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Formula Weight373.218
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Molecular FormulaC14H5F6N5O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 5 mg/mL (13.40 mM)
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SMILESFC(F)(F)c1cc(c2ccc3nc(cn3c2n1)-c1nnco1)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Neumann S, et al. A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor. J Clin Endocrinol Metab. 2011 Feb;96(2):548-54.
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