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RAMX3
CAS No. 1397708-94-9
RAMX3( RAMX-3 | RAMX 3 )
Catalog No. M11660 CAS No. 1397708-94-9
A tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameRAMX3
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NoteResearch use only, not for human use.
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Brief DescriptionA tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM.
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DescriptionA tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM; radioligand displacement assays shows potent negative cooperativity between RAMX3 and chemokine CXCL11, providing a basis for the use of RAMX3 to investigate other potential allosteric modulators.
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In Vitro——
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In Vivo——
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SynonymsRAMX-3 | RAMX 3
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorChemokine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1397708-94-9
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Formula Weight631.693
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Molecular FormulaC33H32T3F4N5O3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-((1-(methyl-t3)piperidin-4-yl)methyl)acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bernat V, et al. ACS Chem Biol. 2014 Nov 21;9(11):2664-77.
2. Bernat V, et al. ChemMedChem. 2012 Aug;7(8):1481-9.
3. Milanos L, et al. Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15277-15281.
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