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Home - Products - GPCR/G Protein - Chemokine Receptor - Plerixafor

Plerixafor

CAS No. 110078-46-1

Plerixafor( JM-3100 | AMD-3100 | SID-791 )

Catalog No. M10387 CAS No. 110078-46-1

Plerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 38 In Stock
10MG 57 In Stock
25MG 102 In Stock
50MG 161 In Stock
100MG 291 In Stock
200MG 462 In Stock
500MG 736 In Stock
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Biological Information

  • Product Name
    Plerixafor
  • Note
    Research use only, not for human use.
  • Brief Description
    Plerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor.
  • Description
    Plerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml; can produce mesenchymal stem cells and endothelial progenitor cells in mice in combination with VEGF; also is an allosteric agonist of CXCR7.Blood Cancer Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    JM-3100 | AMD-3100 | SID-791
  • Pathway
    GPCR/G Protein
  • Target
    Chemokine Receptor
  • Recptor
    CXCL12|CXCR4
  • Research Area
    Cancer
  • Indication
    Blood cancer

Chemical Information

  • CAS Number
    110078-46-1
  • Formula Weight
    502.782
  • Molecular Formula
    C28H54N8
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    C1(CN2CCNCCCNCCNCCC2)=CC=C(CN3CCNCCCNCCNCCC3)C=C1
  • Chemical Name
    1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zabel BA, et al. J Immunol. 2009, 183(5), 3204-3211. 2. De Clercq E, et al. Antimicrob Agents Chemother. 1994 Apr;38(4):668-74. 3. Pitchford SC, et al. Cell Stem Cell. 2009 Jan 9;4(1):62-72.
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