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PEG3-methylamine
CAS No. 282551-10-4
PEG3-methylamine( —— )
Catalog No. M33457 CAS No. 282551-10-4
PEG3-methylamine is a PEG-based linker for PROTACs, joining two essential ligands and facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 28 | Get Quote |
|
| 100MG | 36 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePEG3-methylamine
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NoteResearch use only, not for human use.
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Brief DescriptionPEG3-methylamine is a PEG-based linker for PROTACs, joining two essential ligands and facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
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DescriptionPEG3-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPROTAC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number282551-10-4
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Formula Weight163.22
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Molecular FormulaC7H17NO3
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Purity>98% (HPLC)
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Solubility——
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SMILESOCCOCCOCCNC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
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