Olinciguat

CAS No. 1628732-62-6

Olinciguat( IW-1701 )

Catalog No. M23726 CAS No. 1628732-62-6

Olinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 430 In Stock
10MG 620 In Stock
25MG 972 In Stock
50MG 1332 In Stock
100MG 1764 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Olinciguat
  • Note
    Research use only, not for human use.
  • Brief Description
    Olinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
  • Description
    Olinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    IW-1701
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Guanylate Cyclase
  • Recptor
    Guanylate Cyclase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1628732-62-6
  • Formula Weight
    509.39
  • Molecular Formula
    C21H16F5N7O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (245.39 mM; Need ultrasonic)
  • SMILES
    NC([C@](CNc(nc(-c1nn(Cc(cccc2)c2F)c(-c2nocc2)c1)nc1)c1F)(C(F)(F)F)O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Buys ES, et al. Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad therapeutic potential. Nitric Oxide. 2018 Aug 1;78:72-80.
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