Olinciguat
CAS No. 1628732-62-6
Olinciguat( IW-1701 )
Catalog No. M23726 CAS No. 1628732-62-6
Olinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 430 | In Stock |
|
| 10MG | 620 | In Stock |
|
| 25MG | 972 | In Stock |
|
| 50MG | 1332 | In Stock |
|
| 100MG | 1764 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameOlinciguat
-
NoteResearch use only, not for human use.
-
Brief DescriptionOlinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
-
DescriptionOlinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
-
In Vitro——
-
In Vivo——
-
SynonymsIW-1701
-
PathwayMetabolic Enzyme/Protease
-
TargetGuanylate Cyclase
-
RecptorGuanylate Cyclase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1628732-62-6
-
Formula Weight509.39
-
Molecular FormulaC21H16F5N7O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:125 mg/mL (245.39 mM; Need ultrasonic)
-
SMILESNC([C@](CNc(nc(-c1nn(Cc(cccc2)c2F)c(-c2nocc2)c1)nc1)c1F)(C(F)(F)F)O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Buys ES, et al. Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad therapeutic potential. Nitric Oxide. 2018 Aug 1;78:72-80.
molnova catalog
related products
-
BAY 41-8543
BAY 41-8543 is an NO-independent sGC (soluble guanylyl cyclase) stimulator, inhibits collagen-mediated aggregation in washed human platelets (IC50=90 nM).
-
Vericiguat
Vericiguat (0.01 μM to 100 μM) stimulates recombinant sGC concentration dependently, by 1.7-fold to 57.6-fold.
-
BAY 41-2272
BAY 41-2272 is a potent, NO-independent, orally available soluble guanylate cyclase (sGC) stimulator with IC50 of 0.3 uM.
Cart
sales@molnova.com