OTS447

CAS No. 1356943-67-3

OTS447( —— )

Catalog No. M35684 CAS No. 1356943-67-3

OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 297 In Stock
10MG 471 In Stock
25MG 905 In Stock
50MG 1423 In Stock
100MG 2213 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    OTS447
  • Note
    Research use only, not for human use.
  • Brief Description
    OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .
  • Description
    OTS447 is a potent FLT3 inhibitor with an IC50 of 21 nM (WO2012016082A1, compound 335).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    FLT
  • Recptor
    FLT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1356943-67-3
  • Formula Weight
    466.02
  • Molecular Formula
    C27H32ClN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 12.41 mg/mL (26.63 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)
  • SMILES
    CCN(CC)C1CCC(CC1)Nc1c(cnc2ccc(cc12)-c1ccc(O)c(Cl)c1)C(C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yo Matsuo, et al. Quinoline derivatives and melk inhibitors containing the same. WO2012016082A1.
molnova catalog
related products
  • HM43239 B

    HM43239 is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively.

  • (E/Z)-Zotiraciclib

    (E/Z)-Zotiraciclib inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.

  • HPK1-IN-2

    HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1;IC50<0.05 μΜ).?