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Navamepent
CAS No. 1251537-11-7
Navamepent( —— )
Catalog No. M36377 CAS No. 1251537-11-7
Navamepent (RX-10045) is an analog of resolvin E1 (a dietary-3 polyunsaturated fatty acid metabolite), which has potent anti-inflammatory activity that reduces corneal inflammation, epithelial damage, and accelerates corneal tissue repair.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 471 | Get Quote |
|
| 5MG | 719 | Get Quote |
|
| 10MG | 1007 | Get Quote |
|
| 25MG | 1454 | Get Quote |
|
| 50MG | 1960 | Get Quote |
|
| 100MG | 2583 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameNavamepent
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NoteResearch use only, not for human use.
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Brief DescriptionNavamepent (RX-10045) is an analog of resolvin E1 (a dietary-3 polyunsaturated fatty acid metabolite), which has potent anti-inflammatory activity that reduces corneal inflammation, epithelial damage, and accelerates corneal tissue repair.
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DescriptionNavamepent is an analog of naturally occurring resolvin E1 (a major dietary omega-3 polyunsaturated fatty-acid metabolite) with potent anti-inflammatory and cell survival benefits. Navamepent is highly effective against dry eye and goblet cell loss thereby accelerating tear production. Also, Navamepent can reduce corneal inflammation, epithelial damage, and accelerate corneal tissue repair. In addition, Navamepent can inhibit the release of several key proinflammatory mediators from corneal epithelial cells. Navamepent is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1251537-11-7
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Formula Weight304.38
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Molecular FormulaC18H24O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (328.54 mM; Ultrasonic )
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SMILESC(C[C@@H](C#C/C=C/C=C/[C@@H](CC#C)O)O)CC(OC(C)C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cholkar K, Gilger BC, Mitra AK. Topical delivery of aqueous micellar resolvin E1 analog (RX-10045) [published correction appears in Int J Pharm. 2016 Jul 25;509(1-2):528]. Int J Pharm. 2016;498(1-2):326-334. ?
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