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NNC-0640

CAS No. 307986-98-7

NNC-0640( —— )

Catalog No. M20735 CAS No. 307986-98-7

NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NNC-0640
  • Note
    Research use only, not for human use.
  • Brief Description
    NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.
  • Description
    NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Glucagon Receptor
  • Recptor
    human glucagon receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    307986-98-7
  • Formula Weight
    573.67
  • Molecular Formula
    C29H31N7O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (435.79 mM)
  • SMILES
    CS(=O)(=O)c1cccc(NC(=O)N(Cc2ccc(cc2)C(=O)Nc2nn[nH]n2)c2ccc(cc2)C2CCCCC2)c1
  • Chemical Name
    4-[1-(4-Cyclohexylphenyl)-3-(3-methanesulfonylphenyl)ureidomethyl]-N-(2H-tetrazol-5-yl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Song G Yang D Wang Y et al. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators[J]. Nature 2017.
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