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ND-011992
CAS No. 2446880-46-0
ND-011992( —— )
Catalog No. M36991 CAS No. 2446880-46-0
ND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 141 | Get Quote |
|
| 5MG | 217 | Get Quote |
|
| 10MG | 312 | Get Quote |
|
| 25MG | 517 | Get Quote |
|
| 50MG | 730 | Get Quote |
|
| 100MG | 1017 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameND-011992
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NoteResearch use only, not for human use.
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Brief DescriptionND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I.
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DescriptionND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorMitochondrial Metabolism | Antibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number2446880-46-0
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Formula Weight381.35
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Molecular FormulaC21H14F3N3O
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C=1C2=C(N=CN1)C=CC=C2)C3=CC=C(OC4=CC=C(C(F)(F)F)C=C4)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. K?gi J, et al. Exploring ND-011992, a quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. Sci Rep. 2023;13(1):12226. Published 2023 Jul 28. doi:10.1038/s41598-023-39430-w?
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