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N-Ethyl-p-menthane-3-carboxamide
N-Ethyl-p-menthane-3-carboxamide
CAS No. 39711-79-0
N-Ethyl-p-menthane-3-carboxamide( TRPM8 antagonist WS-3 | Cyclohexanecarboxamide | N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide )
Catalog No. M20582 CAS No. 39711-79-0
N-Ethyl-p-menthane-3-carboxamide is an agonist of TRPM8( EC50 : 3.7 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | 27 | In Stock |
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Biological Information
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Product NameN-Ethyl-p-menthane-3-carboxamide
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NoteResearch use only, not for human use.
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Brief DescriptionN-Ethyl-p-menthane-3-carboxamide is an agonist of TRPM8( EC50 : 3.7 μM).
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DescriptionN-Ethyl-p-menthane-3-carboxamide is an agonist of TRPM8( EC50 : 3.7 μM).
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In Vitro——
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In Vivo——
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SynonymsTRPM8 antagonist WS-3 | Cyclohexanecarboxamide | N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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RecptorTRPM8
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Research Area——
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Indication——
Chemical Information
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CAS Number39711-79-0
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Formula Weight211.34
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Molecular FormulaC13H25NO
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (473.17 mM)
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SMILESCCNC(=O)C1CC(C)CCC1C(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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TRPV3 antagonist 74a
TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.
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Capsazepine
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM).?Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel.?It is therefore considered to be a capsaicin antagonist.
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EIPA
EIPA (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.It is found that EIPA, benzamil, and phenamil rapidly and reversibly block Ca2+-activated TRPP3 channel activation at -50 mV, with IC50s of 143, 10.5, 1.1, and 0.14 μM, respectively.
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