N-Desmethyl-Apalutamide( N-Desmethyl Apalutamide )

Catalog No. M26314 CAS No. 1332391-11-3

N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

N-Desmethyl-Apalutamide
Note

Research use only, not for human use.
Brief Description

N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
Description

N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
In Vitro

——
In Vivo

——
Synonyms

N-Desmethyl Apalutamide
Pathway

Metabolic Enzyme/Protease
Target

P450
Recptor

CYP2C9| HIV
Research Area

——
Indication

——

Chemical Information

CAS Number

1332391-11-3
Formula Weight

463.41
Molecular Formula

C20H13F4N5O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (215.79 mM)
SMILES

NC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C11CCC1)c1cnc(C#N)c(c1)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Chen DF, et al. Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg Med Chem. 1997 Aug;5(8):1715-23.

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