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Molnupiravir

CAS No. 2492423-29-5

Molnupiravir( —— )

Catalog No. M35495 CAS No. 2492423-29-5

Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 32 Get Quote
10MG 52 Get Quote
25MG 66 Get Quote
50MG 112 Get Quote
100MG 177 Get Quote
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Biological Information

  • Product Name
    Molnupiravir
  • Note
    Research use only, not for human use.
  • Brief Description
    Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.
  • Description
    Molnupiravir (EIDD-2801) is an orally bioavailable proagent of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza.
  • In Vitro
    ——
  • In Vivo
    Animal Model:C57BL/6 mice (intranasal infection with SARS-CoV)Dosage:50, 150, 500 mg/kg Administration:Oral; every 12 hours for 3 days Result:Body weight loss is significantly diminished or prevented.Animal Model: Ca/09-infected female ferrets Dosage:7 mg/kg Administration:Oral; twice daily for 3.5 days Result:Shed virus load and duration of fever were significantly reduced.
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Influenza Virus
  • Recptor
    Influenza Virus | SARS-CoV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2492423-29-5
  • Formula Weight
    329.31
  • Molecular Formula
    C13H19N3O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (151.83 mM; Ultrasonic )H2O : 12.5 mg/mL (37.96 mM; Ultrasonic)
  • SMILES
    CC(C)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc\c(=N/O)[nH]c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sheahan TP, et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Sci Transl Med. 2020 Apr 6. pii: eabb5883.?
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