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MZ-242

CAS No. 1862238-01-4

MZ-242( MZ242 | MZ242 )

Catalog No. M12877 CAS No. 1862238-01-4

A novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM.

Purity : >98% (HPLC)

COA

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HNMR

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MSDS

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Biological Information

Product Name

MZ-242
Note

Research use only, not for human use.
Brief Description

A novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM.
Description

A novel potent, selective Sirt2 inhibitor with IC50 of 0.118 uM; displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).
In Vitro

——
In Vivo

——
Synonyms

MZ242 | MZ242
Pathway

Chromatin/Epigenetic
Target

Sirtuin
Recptor

Sirtuin
Research Area

——
Indication

——

Chemical Information

CAS Number

1862238-01-4
Formula Weight

525.646
Molecular Formula

C24H27N7O3S2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CCOC)N=N3)=C2)S1)CSC4=NC(C)=CC(C)=N4
Chemical Name

2-((4,6-dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Szabó A, et al. Sci Rep. 2017 Dec 6;7(1):17070. 2. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.

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