ML115( —— )

Catalog No. M28043 CAS No. 912798-42-6

ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

ML115
Note

Research use only, not for human use.
Brief Description

ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
Description

ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

JAK/STAT Signaling
Target

STAT
Recptor

Apoptosis|Reactive Oxygen Species
Research Area

——
Indication

——

Chemical Information

CAS Number

912798-42-6
Formula Weight

322.75
Molecular Formula

C15H15ClN2O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 20 mg/mL (61.97 mM)
SMILES

COc1cc(NC(=O)c2cc(on2)C2CC2)c(OC)cc1Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Nikoloff N, et al. Flurochloridone-based herbicides induced genotoxicity effects on Rhinella arenarum tadpoles (Anura: Bufonidae). Ecotoxicol Environ Saf. 2014 Feb;100:275-81.

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