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STAT3 inhibitor C188
CAS No. 823828-18-8
STAT3 inhibitor C188( C188 | C-188 | C 188 | STAT3-IN-C188 | Cpd188 | Cpd-188 )
Catalog No. M16058 CAS No. 823828-18-8
A potent, selective STAT3 inhibitor that blocks STAT3 binding to its phosphopeptide ligand (IC50=20 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 196 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSTAT3 inhibitor C188
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective STAT3 inhibitor that blocks STAT3 binding to its phosphopeptide ligand (IC50=20 uM).
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DescriptionA potent, selective STAT3 inhibitor that blocks STAT3 binding to its phosphopeptide ligand (IC50=20 uM) and inhibits IL-6-mediated phosphorylation of STAT3; inhibits nuclear translocation of phosphorylated Stat3 with IC50 of 39 uM, induces apoptosis preferentially of breast cancer cell lines with constitutive Stat3 activation.
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In Vitro——
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In Vivo——
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SynonymsC188 | C-188 | C 188 | STAT3-IN-C188 | Cpd188 | Cpd-188
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number823828-18-8
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Formula Weight433.449
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Molecular FormulaC19H15NO7S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (230.71 mM)
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SMILESO=C(O)C1=CC=C(S(=O)(NC2=C3C=CC=CC3=C(O)C(SCC(O)=O)=C2)=O)C=C1
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Chemical Name4-(N-(3-((carboxymethyl)thio)-4-hydroxynaphthalen-1-yl)sulfamoyl)benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xu X, et al. PLoS One. 2009;4(3):e4783.
molnova catalog
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