MK-9470( MK9470 )

Catalog No. M16778 CAS No. 945850-36-2

MK-9470 is a potent, selective cannabinoid CB1 receptor (CB1R) inverse agonist with IC50 of 0.7 nM.

Purity : >98% (HPLC)

COA

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HNMR

HPLC

MSDS

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Biological Information

Product Name

MK-9470
Note

Research use only, not for human use.
Brief Description

MK-9470 is a potent, selective cannabinoid CB1 receptor (CB1R) inverse agonist with IC50 of 0.7 nM.
Description

MK-9470 is a potent, selective cannabinoid CB1 receptor (CB1R) inverse agonist with IC50 of 0.7 nM, 18F MK-9470 has been developed for use in human brain imaging.
In Vitro

——
In Vivo

——
Synonyms

MK9470
Pathway

GPCR/G Protein
Target

Cannabinoid Receptor
Recptor

Cannabinoid Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

945850-36-2
Formula Weight

471.59
Molecular Formula

C29H33N3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

CC1=CN=C(C=C1)OC(C)(C)C(=O)NC(C)C(CC2=CC=C(C=C2)OCCF)C3=CC=CC(=C3)C#N
Chemical Name

N-[(2S,3S)-3-(3-cyanophenyl)-4-(4-ethoxyphenyl)butan-2-yl]-2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Burns HD, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9800-5. 2. Van Laere K, et al. J Nucl Med. 2008 Mar;49(3):439-45. 3. Gérard N, et al. J Mol Neurosci. 2010 Oct;42(2):162-7.

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