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GAT-100
CAS No. 1663564-42-8
GAT-100( GAT100 )
Catalog No. M12537 CAS No. 1663564-42-8
GAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1053 | Get Quote |
|
| 50MG | 2142 | Get Quote |
|
| 100MG | 2790 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGAT-100
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NoteResearch use only, not for human use.
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Brief DescriptionGAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM.
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DescriptionGAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM, does not exhibit inverse agonism; GAT-100 is a covalent probe for mapping structure-function correlates characteristic of the druggable CB1R allosteric space.
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In Vitro——
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In Vivo——
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SynonymsGAT100
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCannabinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1663564-42-8
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Formula Weight432.59
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Molecular FormulaC25H28N4OS
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C(N1)=C(CC)C2=C1C=CC(N=C=S)=C2)NCCC3=CC=C(N4CCCCC4)C=C3
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Chemical Name3-Ethyl-5-isothiocyanato-N-(4-(piperidin-1-yl)phenethyl)-1H-indole-2-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kulkarni PM, et al. J Med Chem. 2016 Jan 14;59(1):44-60.
2. Laprairie RB, et al. ACS Chem Neurosci. 2016 Jun 15;7(6):776-98.
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