Laprafylline is a xanthine compound with inhibitory effects on bronchoconstriction in vivo and antitumor activity.

L524-0366 is a TWEAK-Fn14 signaling cascade inhibitor.L524-0366 mitigated maladaptive remodeling with TAC. TWEAK induced secretion of the pro-inflammatory chemokine, monocyte chemoattractant protein 1 from WT but not Fn14-/-?fibroblasts in vitro, in part through activation of non-canonical NF-κB signaling.

2-Phthalimidehydroxy-acetic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.