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MitoBloCK-11?(MB-11)

CAS No. 413606-16-3

MitoBloCK-11?(MB-11)( —— )

Catalog No. M22985 CAS No. 413606-16-3

MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 114 In Stock
5MG 98 In Stock
10MG 151 In Stock
25MG 250 In Stock
50MG 345 In Stock
100MG 463 In Stock
200MG 626 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    MitoBloCK-11?(MB-11)
  • Note
    Research use only, not for human use.
  • Brief Description
    MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
  • Description
    MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    mitochondrial protein import
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    413606-16-3
  • Formula Weight
    434.3
  • Molecular Formula
    C17H12BrN3O4S?
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (287.85 mM)
  • SMILES
    O=C(NN=CC1=CC=C([N+]([O-])=O)S1)COC2=C3C=CC=CC3=C(Br)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Conti, M. (2018). Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy. UCLA. 2. Miyata N, et al. J Biol Chem. 2017 Mar 31;292(13):5429-5442. View Related Products by Target Other Target
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