Antagonist G

Research use only, not for human use.

Antagonist G is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy.

Antagonist G is an anticancer peptide and is also a broad spectrum neuropeptide growth factor antagonist.

Antagonist G (0-100 μM) induces apoptosis is redox-sensitive and caspase-dependently in SCLC cells.Antagonist G activates JNK1 in SCLC cells.Antagonist G is not intrinsically a free radical oxygen donor but stimulates free radical generation specifically within SCLC cells (6.2-fold) and increases the activity of the redox-sensitive transcription factor AP-1 by 61%.Cell Viability Assay Cell Line:SCLC cell lines NCI-H69, NCI-H510 and CHO-K1 cells.Concentration:0-100 μM.Incubation Time:24 h.

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Others

Other Targets

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115150-59-9

951.2

C49H62O6N12S

>98% (HPLC)

H2O : 50 mg/mL (52.57 mM; ultraphonic)

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(-20℃)

With Ice Pack

≥ 2 years