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Ulinastatin

CAS No. 80449-31-6

Ulinastatin( Bikunin | Mingin | Miraclid | Trypsin inhibitor UTI | Urinary trypsin inhibitor 1 | Urinastatin )

Catalog No. M24803 CAS No. 80449-31-6

Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 39 In Stock
25MG 82 In Stock
50MG 127 In Stock
100MG 207 In Stock
200MG 306 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Ulinastatin
  • Note
    Research use only, not for human use.
  • Brief Description
    Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.
  • Description
    Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.
  • In Vitro
    Western Blot Analysis Cell Line:Human lung epithelial BEAS-2B cells Concentration:500 U, 2500 U, 5000 U Incubation Time:24 hours Result:Markedly attenuated TLR4 expression and NF-κB activation in LPS-stimulated BEAS-2B cells.
  • In Vivo
    Animal Model:Male C57BL/6 mice (8-10 weeks old, 18-22 g)Dosage:10000 U/kg Administration:i.v.; twice (1 h before and 6 h after LPS treatment)Result:Significantly protected animals from LPS-induced ALI.
  • Synonyms
    Bikunin | Mingin | Miraclid | Trypsin inhibitor UTI | Urinary trypsin inhibitor 1 | Urinastatin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Kunitz-type serine protease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    80449-31-6
  • Formula Weight
    ——
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 10 mg/mL
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nakahama H , Kuribayashi K , Sugita M , et al. Cytoprotective effect of ulinastatin, a Kunitz-type protease inhibitor, on hypoxic injury in L2 cells treated with antimycin A via stabilization of lysosomal fragility.[J]. Pulmonary Pharmacology & Therapeutics, 1999, 12(1):1-6.
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