Heliosupine, heliosupine N-oxide, 3 ′-O-acetylheliosupine N-oxide,and 7-O- angeloylechinatine N-oxide show inhibition activity against the acetylcholinesterase(AChE), with IC50 0.53-0.60 mM. Heliosupine can deter feeding by the polyphagous larvae of Spodoptera exigua.

Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-NH-PEG3-propionic acid incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

Leteprinim is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from astrocytes.