Tea polyphenol also called green tea extract are a mixture of chemical compounds such as flavanoids and tannins found naturally in tea. Polyphenols are powerful antioxidants which can reduce the risk of developing coronary artery disease and a number of other health problems.

D-Leu-Leu|H-D-Leu-Leu-OH

PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes . PBIT, which inhibits JARID1B with an IC50 of about 3 μm in vitro.