Cart
sales@molnova.com
α-Conotoxin EI
CAS No. 170663-33-9
α-Conotoxin EI( ——— )
Catalog No. M41034 CAS No. 170663-33-9
α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. α-Conotoxin EI can block muscle and ganglionic receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | Get Quote | Get Quote |
|
| 50MG | Get Quote | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product Nameα-Conotoxin EI
-
NoteResearch use only, not for human use.
-
Brief Descriptionα-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. α-Conotoxin EI can block muscle and ganglionic receptors.
-
DescriptionSelective antagonist of neuromuscular nicotinic receptors α1β1γδ
-
In Vitroα-Conotoxin EI (10 μM) blocks muscle and ganglionic receptors, but less potent for the central nevous system receptor.α-Conotoxin EI (10 μM) blocks the α1β1γδ receptors with a τon of 4.9 s, and blocks the α3β4 receptor with a τon of 11 s.
-
In Vivoα-Conotoxin EI (intraperitoneal injection) into mice induces muscular weakness, followed by flaccid paralysis and ultimately death.
-
Synonyms———
-
PathwayEndocrinology/Hormones
-
TargetAChR
-
Recptorneuromuscular nicotinic receptors α1β1γδ
-
Research Area———
-
Indication———
Chemical Information
-
CAS Number170663-33-9
-
Formula Weight2093.37
-
Molecular FormulaC83H125N27O27S5
-
Purity>98% (HPLC)
-
Solubility———
-
SMILES———
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Martinez JS, et al. alpha-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity. Biochemistry. 1995 Nov 7;34(44):14519-26.?
molnova catalog
related products
-
VASICINE
Vasicine is oxytocic and abortifacient agents.Vasicine a potential natural cholinesterase inhibitor has been in development for treatment of Alzheimer's disease.
-
5-Hydroxy-1,7-diphen...
5-Hydroxy-1, 7-diphenyl-6-hepten-3-one has antioxidant activity.
-
Nicotine Ditartrate
(?)-Nicotine is the dominant form of the natural alkaloid nicotine. It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties. (?)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode thus nicotine is typically synthesized as (?)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.
