Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC50=303 nM).

Exoticin shows antinociceptive and neuropharmacological activities, it could be considered as a suitable candidate for the development of analgesic and anxiolytic agents.

(+)-Isolariciresinol is extracted from Radix Isatidis and shows antioxidant and anti-inflammatory activities and can be used in studies about rheumatism.