L-Ascorbic Acid 2-Phosphate Sesquimagnesium Salt Hydrate (~15% Inorganics)

Research use only, not for human use.

L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation.

L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs).

L-Ascorbic acid 2-phosphate (0.1-1.5 mM; 2 to 3 weeks with medium exchange every 2 to 3 days) magnesium hydrate significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc)achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation withEGF and/or insulin does not have any additional effect .L-Ascorbic acid 2-phosphate (50 μM-250 μM) magnesium hydrate is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 μM AsA2-P and 10 nM dexamethasone (Dex), and 250 μM AsA2-P and 5 nM Dex.Cell Proliferation Assay Cell Line:Human corneal endothelial cells (HCECs) Concentration:0.1 mM; 0.3 mM; 1.5 mM Incubation Time:2 to 3 weeks with medium exchange every 2 to 3 days Result:Stimulated HCEC cells growth.

———

———

Others

Other Targets

———

———

———

1713265-25-8

———

———

>98% (HPLC)

H2O : 5 mg/mL (ultraphonic (<60°C))

———

——

(-20℃)

With Ice Pack

≥ 2 years