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(S,S)-Secoisolariciresinol diglucoside

CAS No. 257930-74-8

(S,S)-Secoisolariciresinol diglucoside( —— )

Catalog No. M37778 CAS No. 257930-74-8

(S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 48 In Stock
5MG 77 In Stock
10MG 133 In Stock
25MG 256 In Stock
50MG 356 In Stock
100MG 609 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    (S,S)-Secoisolariciresinol diglucoside
  • Note
    Research use only, not for human use.
  • Brief Description
    (S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis.
  • Description
    Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects.
  • In Vitro
    Secoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals.Secoisolariciresinol diglucoside (1-50 μM; 24 h) attenuates human monocyte adhesion to and migration across human brain endothelial monolayers.
  • In Vivo
    Secoisolariciresinol diglucoside (4 mg/mouse; a single p.o.) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation.Animal Model:Hand feeding mice (10 weeks old, male) are injected with TNFα Dosage:4 mg/mouse Administration:P.o. 2 h before i.c. administration of TNFα Result:Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Antioxidant
  • Recptor
    Antioxidant
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    257930-74-8
  • Formula Weight
    686.7
  • Molecular Formula
    C32H46O16
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : ≥ 100 mg/mL (145.62 mM)
  • SMILES
    [C@@H]([C@H](CC1=CC(OC)=C(O)C=C1)CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)(CC3=CC(OC)=C(O)C=C3)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mishra OP, et al. Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs). Bioorg Med Chem Lett. 2013 Oct 1;23(19):5325-8.?
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