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Home - Products - Microbiology/Virology - Parasite - 5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole

5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole

CAS No. 2863687-18-5

5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole( —— )

Catalog No. M37686 CAS No. 2863687-18-5

Antileishmanial agent-2 is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 155 In Stock
5MG 149 In Stock
10MG 220 In Stock
25MG 337 In Stock
50MG 462 In Stock
100MG 619 In Stock
200MG 835 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole
  • Note
    Research use only, not for human use.
  • Brief Description
    Antileishmanial agent-2 is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.
  • Description
    Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Parasite
  • Recptor
    Parasite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2863687-18-5
  • Formula Weight
    350.21
  • Molecular Formula
    C15H16BrN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(C)(C)(C)C1=CC=C(C=2N=C(ON2)C3ONC(Br)=C3)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Galbiati A, et al. Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds. ACS Med Chem Lett. 2021 Oct 13;12(11):1726-1732. ?
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