Minodronic acid( —— )

Catalog No. M37531 CAS No. 180064-38-4

Minodronic acid(YM-529) is a P2X2/3 receptor antagonist with anticancer activity, directly or indirectly inhibiting the proliferation of cancer cells and inducing apoptosis.

Purity : >98% (HPLC)

COA

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HNMR

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MSDS

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Size	Price / USD	Stock	Quantity
10MG	38	Get Quote
25MG	59	Get Quote
50MG	86	Get Quote
100MG	116	Get Quote
500MG	293	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Minodronic acid
Note

Research use only, not for human use.
Brief Description

Minodronic acid(YM-529) is a P2X2/3 receptor antagonist with anticancer activity, directly or indirectly inhibiting the proliferation of cancer cells and inducing apoptosis.
Description

Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

P2X Receptor
Recptor

P2X Receptor | Apoptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

180064-38-4
Formula Weight

322.15
Molecular Formula

C9H12N2O7P2
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : 5 mg/mL (15.52 mM) DMSO : < 1 mg/mL (insoluble or slightly soluble)
SMILES

OC(Cc1cnc2ccccn12)(P(O)(O)=O)P(O)(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Sato K, et al. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br J Cancer. 2006 Nov 20;95(10):1354-61.?

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