2-Deoxy-D-galactose

Research use only, not for human use.

2-Deoxy-D-galactose is a glucose analog and glucose antagonist that inhibits the maintenance of hippocampal LTP and can suppress tumor growth by inhibiting the glycolytic process.

2-Deoxy-D-galactose is a glucose analog. 2-Deoxy-D-galactose inhibits glycolysis to inhibits tumor growth. 2-Deoxy-D-galactose is a substance interfering with the fucosylation of glycomacromolecules and impairing memory consolidation in various learning tasks. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo.

2-Deoxy-D-galactose (1 mM/L; 5 h) is rapid phosphorylation during the first 30 min and decreases to approximately 20% of this rate during the subsequent hours in ascites hepatoma cells.

2-Deoxy-D-galactose (380 mg/kg; i.p.; for 6 times) strongly decreases contents of UMP, UDPG, and UDP galactose in rat livers.2-Deoxy-D-galactose (2-8 μM; intracerebroventricularly injection; once) shows PAR impairment 30 min before the acquisition trial a dose of 4 μM and 15 min delay after do-gal administration.Animal Model:Male adult Wistar rats with passive avoidance response (PAR) acquisition trial Dosage:2, 4 and 8 μM Administration:Intracerebroventricularly injection; 2-8 μM; once Result:Exhibited PAR disruption at a dose of 4 μM.

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Others

Other Targets

Others

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1949-89-9

164.16

C6H12O5

>98% (HPLC)

In Vitro:?H2O : 250 mg/mL (1522.90 mM; Ultrasonic) Methanol : 125 mg/mL (761.45 mM; Ultrasonic)

OC[C@@H](O)[C@H](O)[C@H](O)CC=O

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(-20℃)

With Ice Pack

≥ 2 years