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RGB-1
CAS No. 930455-91-7
RGB-1( —— )
Catalog No. M37294 CAS No. 930455-91-7
RGB-1, a small molecule that selectively stabilizes the RNA G-quadruplex structure, enhances G-quadruplex-mediated inhibition of RNA translation in mammalian cells and reduces NRAS proto-oncogene expression in breast cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 758 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameRGB-1
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NoteResearch use only, not for human use.
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Brief DescriptionRGB-1, a small molecule that selectively stabilizes the RNA G-quadruplex structure, enhances G-quadruplex-mediated inhibition of RNA translation in mammalian cells and reduces NRAS proto-oncogene expression in breast cancer cells.
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DescriptionRGB-1 is a polycyclic aromatic hydrocarbon molecule and a stabilizer of RNA G-quadruplexes. RGB-1 can promote the inhibition of RNA translation and reduce the expression of NRAS proto-oncogene in breast cancer cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number930455-91-7
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Formula Weight460.49
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Molecular FormulaC22H12N4O4S2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1C2=C(N=C3N1CC4=NC=5SC=C(C=6OC=CC6)C5C(=O)N4C3)SC=C2C=7OC=CC7
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Katsuda Y, et al. A Small Molecule That Represses Translation of G-Quadruplex-Containing mRNA. J Am Chem Soc. 2016 Jul 27;138(29):9037-40.
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