mSIRK( —— )

Catalog No. M37262 CAS No. 593267-11-9

mSIRK (G-Protein βγ Binding Peptide) is a cell-permeable activator of ERK 1/2 with an EC50 of 2.5-5 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	77	In Stock
10MG	117	In Stock
25MG	188	In Stock
50MG	276	In Stock
100MG	421	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
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Biological Information

Product Name

mSIRK
Note

Research use only, not for human use.
Brief Description

mSIRK (G-Protein βγ Binding Peptide) is a cell-permeable activator of ERK 1/2 with an EC50 of 2.5-5 μM.
Description

mSIRK (G-Protein βγ Binding Peptide) is an cell-permeable activator of ERK1/2, with EC50 of 2.5-5 μM. mSIRK disrupts the interaction between α and βγ subunits and promotes α subunit dissociation without stimulating nucleotide exchange.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

MAPK/ERK Signaling
Target

ERK
Recptor

ERK
Research Area

——
Indication

——

Chemical Information

CAS Number

593267-11-9
Formula Weight

1948.31
Molecular Formula

C93H150N20O25
Purity

>98% (HPLC)
Solubility

——
SMILES

C([C@H](CC1=CC=C(O)C=C1)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCCCCCC)=O)CO)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCCN)=O)C)=O)CC(C)C)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC(C)C)=O)=O)(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)CC(O)=O)=O)CCC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Farida Goubaeva, et al. Stimulation of Cellular Signaling and G Protein Subunit Dissociation by G Protein βγ Subunit-binding Peptides. J Biol Chem. 2003 May 30;278(22):19634-41.?

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