Cart
sales@molnova.com
Sirtuin-1 inhibitor 1
CAS No. 945114-10-3
Sirtuin-1 inhibitor 1( —— )
Catalog No. M37256 CAS No. 945114-10-3
Sirtuin-1 inhibitor 1 is an inhibitor against deacetylase-1 (Sirtuin-1) and can be used to study senescence and cell death in the organism.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 150 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSirtuin-1 inhibitor 1
-
NoteResearch use only, not for human use.
-
Brief DescriptionSirtuin-1 inhibitor 1 is an inhibitor against deacetylase-1 (Sirtuin-1) and can be used to study senescence and cell death in the organism.
-
DescriptionSirtuin-1 inhibitor 1 (Compound 8) is an inhibitor of Sirtuin-1 that plays important roles in obesity-induced diabetes and aging-related diseases.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetSirtuin
-
RecptorSirtuin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number945114-10-3
-
Formula Weight331.37
-
Molecular FormulaC20H17N3O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 20.83 mg/mL (62.86 mM; Ultrasonic (<60°C)
-
SMILESO=C(NC=1C=CC=CC1)NC2=CC=C(C=C2)NC(=O)C=3C=CC=CC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Anastasiia Gryniukova, et al. AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1. J Med Chem. 2023 Aug 10;66(15):10241-10251.?
molnova catalog
related products
-
ADTL-SA1215
ADTL-SA1215 is a selective SIRT3 activator with SIRT3 deacetylase activity that inhibits the proliferation and migration of human breast cancer MDA-MB-231 cells through the SIRT3-driven autophagy/mitochondrial autophagy signaling pathway, and can be used in the study of triple negative breast cancer.
-
Ophiopogonin D (b)
Ophiopogonin D' can activate SIRT1 in a dose-dependent manner. Ophiopogonin D' also noncompetitively inhibits UGT1A6 and UGT1A10.
-
SirReal1
A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM.
