Estrogen receptor antagonist 8( —— )

Catalog No. M37205 CAS No. 2889370-92-5

Estrogen receptor antagonist 8 acts as an estrogen receptor (ER) antagonist with anti-uterine activity and potential anti-tumorigenic activity and can be used to study ovarian dysfunction.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Estrogen receptor antagonist 8
Note

Research use only, not for human use.
Brief Description

Estrogen receptor antagonist 8 acts as an estrogen receptor (ER) antagonist with anti-uterine activity and potential anti-tumorigenic activity and can be used to study ovarian dysfunction.
Description

Estrogen receptor antagonist 8 is a potent ER-antagonist with in vivo anti-uterotrophic potential (EC50 = 4.160 μM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Endocrinology/Hormones
Target

Estrogen Receptor/ERR
Recptor

Estrogen/progestogen Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

2889370-92-5
Formula Weight

427.45
Molecular Formula

C25H21N3O4
Purity

>98% (HPLC)
Solubility

——
SMILES

O=N(=O)C1=CC=C(C=C1)N2N=C3C=4C=CC(OC)=CC4CCC3=C2C=5C=CC(OC)=CC5
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Mahmoud A Ragab, et al. Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity. Bioorg Chem. 2022 Feb;119:105554.?

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