6PPD-Q

CAS No. 2754428-18-5

6PPD-Q( —— )

Catalog No. M37188 CAS No. 2754428-18-5

6PPD-Q (6PPD-Quinone), a contaminant present in the environment and soil, is a derivative of the tire antioxidant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), which impairs the quality of spermatozoa in mice and induces impaired male fertility.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    6PPD-Q
  • Note
    Research use only, not for human use.
  • Brief Description
    6PPD-Q (6PPD-Quinone), a contaminant present in the environment and soil, is a derivative of the tire antioxidant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), which impairs the quality of spermatozoa in mice and induces impaired male fertility.
  • Description
    6PPD-Q (6PPD-Quinone) is an endogenous metabolite that can be found in human urine and can also commonly found in the environment.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2754428-18-5
  • Formula Weight
    298.38
  • Molecular Formula
    C18H22N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 5 mg/mL (16.76 mM; Ultrasonic (<60°C)
  • SMILES
    O=C1C=C(NC(C)CC(C)C)C(=O)C=C1NC=2C=CC=CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Du B, et al. First report on the occurrence of N-(1, 3-dimethylbutyl)-N’-phenyl-p-phenylenediamine (6PPD) and 6PPD-quinone as pervasive pollutants in human urine from south China. Environ Sci Technol Lett, 2022, 9(12): 1056-1062.
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