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Cisd2 agonist 1
CAS No. 2916371-54-3
Cisd2 agonist 1( —— )
Catalog No. M37138 CAS No. 2916371-54-3
Cisd2 agonist 1 is a potent CDGSH iron-sulfur structural domain 2 (CISD2) agonist (EC50: 34 nM) with potential anticancer activity for the study of non-alcoholic fatty liver disease (NAFLD).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 170 | In Stock |
|
| 5MG | 155 | In Stock |
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| 10MG | 250 | In Stock |
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| 25MG | 511 | In Stock |
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| 50MG | 830 | In Stock |
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| 100MG | 1135 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2279 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCisd2 agonist 1
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NoteResearch use only, not for human use.
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Brief DescriptionCisd2 agonist 1 is a potent CDGSH iron-sulfur structural domain 2 (CISD2) agonist (EC50: 34 nM) with potential anticancer activity for the study of non-alcoholic fatty liver disease (NAFLD).
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DescriptionCisd2 agonist 1 (Compound 4q) is a Cisd2 agonist (EC50: 34 nM). Cisd2 agonist 1 enhances the Cisd2 expression and improves the pathological changes in the fatty livers. Cisd2 agonist 1 has good metabolic stability. Cisd2 agonist 1 can be used for research of NAFLD.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2916371-54-3
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Formula Weight308.33
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Molecular FormulaC14H13FN2O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (324.33 mM; Ultrasonic )
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SMILESO=C(OC)C1=C(SC(C(=O)NC2=CC=C(F)C=C2)=C1C)N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yao CH, et al. Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease. Eur J Med Chem. 2023 Oct 5;258:115583.?
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