Cart
sales@molnova.com
UCL-TRO-1938
CAS No. 2919575-27-0
UCL-TRO-1938( —— )
Catalog No. M37137 CAS No. 2919575-27-0
UCL-TRO-1938 is a subtype-selective PI3Kα allosteric activator with cardioprotective and neuroregenerative effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 117 | In Stock |
|
| 5MG | 117 | In Stock |
|
| 10MG | 187 | In Stock |
|
| 25MG | 392 | In Stock |
|
| 50MG | 616 | In Stock |
|
| 100MG | 986 | In Stock |
|
| 200MG | 1321 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameUCL-TRO-1938
-
NoteResearch use only, not for human use.
-
Brief DescriptionUCL-TRO-1938 is a subtype-selective PI3Kα allosteric activator with cardioprotective and neuroregenerative effects.
-
DescriptionUCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of approximately 60 μM. UCL-TRO-1938 can induce cell proliferation and has cardioprotective and neural regeneration effects.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayPI3K/Akt/mTOR signaling
-
TargetPI3K
-
RecptorPI3K
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2919575-27-0
-
Formula Weight456.58
-
Molecular FormulaC27H32N6O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (109.51 mM; Ultrasonic (<80°C)
-
SMILESO=C(N1C=2C(=CC=CC2CC1)NC=3C=CN=C(C3)NC4=CC=C(C=C4)N5CCN(CC)CC5)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Grace Q Gong, et al. A small-molecule PI3Kα activator for cardioprotection and neuroregeneration. Nature. 2023 Jun;618(7963):159-168.?
molnova catalog
related products
-
SN-32976
SN-32976 is a novel, potent and selective class I PI3K and mTOR inhibitor.
-
SF2523
A novel potent, dual inhibitor of PI3K and BRD4 with IC50 of 241, 34, 158 nM for BRD4 (BD1), PI3Kα and PI3Kγ, respectively.
-
mTOR inhibitor 9d
mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia, skin cancer, breast cancer, lung cancer and colon cancer.
