Cart
sales@molnova.com
UCL-TRO-1938
CAS No. 2919575-27-0
UCL-TRO-1938( —— )
Catalog No. M37137 CAS No. 2919575-27-0
UCL-TRO-1938 is a subtype-selective PI3Kα allosteric activator with cardioprotective and neuroregenerative effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 117 | Get Quote |
|
| 10MG | 187 | Get Quote |
|
| 25MG | 380 | Get Quote |
|
| 50MG | 609 | Get Quote |
|
| 100MG | 954 | Get Quote |
|
| 200MG | 1278 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameUCL-TRO-1938
-
NoteResearch use only, not for human use.
-
Brief DescriptionUCL-TRO-1938 is a subtype-selective PI3Kα allosteric activator with cardioprotective and neuroregenerative effects.
-
DescriptionUCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of approximately 60 μM. UCL-TRO-1938 can induce cell proliferation and has cardioprotective and neural regeneration effects.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayPI3K/Akt/mTOR signaling
-
TargetPI3K
-
RecptorPI3K
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2919575-27-0
-
Formula Weight456.58
-
Molecular FormulaC27H32N6O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (109.51 mM; Ultrasonic (<80°C)
-
SMILESO=C(N1C=2C(=CC=CC2CC1)NC=3C=CN=C(C3)NC4=CC=C(C=C4)N5CCN(CC)CC5)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Grace Q Gong, et al. A small-molecule PI3Kα activator for cardioprotection and neuroregeneration. Nature. 2023 Jun;618(7963):159-168.?
molnova catalog
related products
-
GSK-2636771
GSK2636771 is a potent, orally bioavailable, PI3Kβ-selective inhibitor, sensitive to PTEN null cell lines. Phase 1/2a.
-
TG6-10-1
TG6-10-1 is an EP2 antagonist.
-
I-OMe-Tyrphostin AG ...
I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 μM).
