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Home - Products - MAPK/ERK Signaling - ERK - ERK5-IN-6

ERK5-IN-6

CAS No. 2734916-64-2

ERK5-IN-6( —— )

Catalog No. M37089 CAS No. 2734916-64-2

ERK5-IN-6 is a potent inhibitor of ERK5 kinase.ERK5-IN-6 exhibits antiproliferative activity, anticonvulsant activity, and antitumor activity, and can be used in the study of central nervous system-related disorders.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ERK5-IN-6
  • Note
    Research use only, not for human use.
  • Brief Description
    ERK5-IN-6 is a potent inhibitor of ERK5 kinase.ERK5-IN-6 exhibits antiproliferative activity, anticonvulsant activity, and antitumor activity, and can be used in the study of central nervous system-related disorders.
  • Description
    ERK5-IN-6 (compound 5J)is an ERK5 kinase inhibitor with anticancer activity. ERK5-IN-6 exhibits good anti-proliferative activity with the IC50 value of 4.56 μg/mL for A549 cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    ERK
  • Recptor
    ERK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2734916-64-2
  • Formula Weight
    339.43
  • Molecular Formula
    C23H21N3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N1=CC=CC2=C1NC=C2C3=CCN(CC=4C=CC=5C=CC=CC5C4)CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Qin Zhang, et al. Design, synthesis and SAR of novel 7-azaindole derivatives as potential Erk5 kinase inhibitor with anticancer activity. Bioorg Med Chem. 2023 Oct 14:95:117503. ?
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