FC-116

CAS No. 2417298-29-2

FC-116( —— )

Catalog No. M36931 CAS No. 2417298-29-2

FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 129 In Stock
5MG 113 In Stock
10MG 187 In Stock
25MG 330 In Stock
50MG 461 In Stock
100MG 607 In Stock
200MG 826 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    FC-116
  • Note
    Research use only, not for human use.
  • Brief Description
    FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.
  • Description
    FC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis | Microtubule Associated
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2417298-29-2
  • Formula Weight
    369.39
  • Molecular Formula
    C21H20FNO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=C(/C(=O)C1=CC(OC)=C(OC)C(OC)=C1)\C)\C=2C=3C(NC2)=CC(F)=CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Liu X, et al. Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy. Eur J Med Chem. 2023 Sep 5;257:115540.?
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