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FC-116
CAS No. 2417298-29-2
FC-116( —— )
Catalog No. M36931 CAS No. 2417298-29-2
FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 129 | In Stock |
|
| 5MG | 113 | In Stock |
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| 10MG | 187 | In Stock |
|
| 25MG | 330 | In Stock |
|
| 50MG | 461 | In Stock |
|
| 100MG | 607 | In Stock |
|
| 200MG | 826 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFC-116
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NoteResearch use only, not for human use.
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Brief DescriptionFC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.
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DescriptionFC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis | Microtubule Associated
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Research Area——
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Indication——
Chemical Information
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CAS Number2417298-29-2
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Formula Weight369.39
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Molecular FormulaC21H20FNO4
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Purity>98% (HPLC)
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Solubility——
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SMILESC(=C(/C(=O)C1=CC(OC)=C(OC)C(OC)=C1)\C)\C=2C=3C(NC2)=CC(F)=CC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Liu X, et al. Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy. Eur J Med Chem. 2023 Sep 5;257:115540.?
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