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MyD88-IN-1
CAS No. 2911609-80-6
MyD88-IN-1( —— )
Catalog No. M36865 CAS No. 2911609-80-6
MyD88-IN-1 is a potent MyD88 inhibitor with anti-inflammatory activity, inhibiting downstream pathways such as the NF-κB pathway of the Toll-like receptor (TLR) and interleukin-1 (IL-1) receptor family.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 164 | In Stock |
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| 5MG | 150 | In Stock |
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| 10MG | 225 | In Stock |
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| 25MG | 373 | In Stock |
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| 50MG | 454 | In Stock |
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| 100MG | 646 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1330 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMyD88-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionMyD88-IN-1 is a potent MyD88 inhibitor with anti-inflammatory activity, inhibiting downstream pathways such as the NF-κB pathway of the Toll-like receptor (TLR) and interleukin-1 (IL-1) receptor family.
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DescriptionMyD88-IN-1 is a potent MyD88 inhibitor. MyD88-IN-1 inhibits the interaction of TLR4 and MyD88 and suppressed the NF-κB pathway. MyD88-IN-1 can be used in research of cancer and inflammatory.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetIL Receptor
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RecptorIL Receptor | NF-κB | MyD88 | TLR
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Research Area——
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Indication——
Chemical Information
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CAS Number2911609-80-6
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Formula Weight528.54
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Molecular FormulaC23H24N6O7S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (189.20 mM; Ultrasonic )
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SMILESN(=O)(=O)C1=C(C=CC(S(NC=2C=CC(OC)=NC2)(=O)=O)=C1)N3CCN(CC4=CC(N(=O)=O)=CC=C4)CC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chen P, et, al. Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen. J Med Chem. 2023 May 25;66(10):6938-6958.?
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