ARRY-797
CAS No. 1036404-17-7
ARRY-797( ARRY-371797 | ARRY-797 )
Catalog No. M28777 CAS No. 1036404-17-7
ARRY-797 is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 131 | Get Quote |
|
| 10MG | 218 | Get Quote |
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| 25MG | 385 | Get Quote |
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| 50MG | 655 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameARRY-797
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NoteResearch use only, not for human use.
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Brief DescriptionARRY-797 is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.
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DescriptionARRY-797 is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.(In Vivo):ARRY-797 inhibits the growth of RPMI-8226 Human Multiple Myeloma Cells. ARRY-371797 prevented left ventricular dilatation and deterioration of fractional shortening compared with placebo-treated mice.
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In Vitro——
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In Vivo——
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SynonymsARRY-371797 | ARRY-797
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PathwayApoptosis
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TargetIL Receptor
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RecptorMicrotubule/Tubulin
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Research Area——
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Indication——
Chemical Information
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CAS Number1036404-17-7
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Formula Weight——
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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NFAT inhibitor, Cell...
NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. Cell permeable.
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Mepolizumab
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