Cart
sales@molnova.com
Nemvaleukin alfa
CAS No. 2315268-27-8
Nemvaleukin alfa( —— )
Catalog No. M36815 CAS No. 2315268-27-8
Nemvaleukin alfa (ALKS 4230) is an interleukin 2 fusion protein, a selective agonist of the medium-affinity IL-2 receptor, produced by fusion of the IL-2Ralpha subunit of the circularly arranged interleukin-2 (IL-2) and IL-2 receptor (IL-2R) complexes, which drives antitumor Immunity and inhibits tumor growth in small cell lung cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1017 | In Stock |
|
| 10MG | 1634 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNemvaleukin alfa
-
NoteResearch use only, not for human use.
-
Brief DescriptionNemvaleukin alfa (ALKS 4230) is an interleukin 2 fusion protein, a selective agonist of the medium-affinity IL-2 receptor, produced by fusion of the IL-2Ralpha subunit of the circularly arranged interleukin-2 (IL-2) and IL-2 receptor (IL-2R) complexes, which drives antitumor Immunity and inhibits tumor growth in small cell lung cancer.
-
DescriptionNemvaleukin alfa (ALKS 4230) is a IL-2 fusion protein that selectively binds to intermediate-affinity IL-2R. Nemvaleukin alfa is an activator of NK and effector T cells. Nemvaleukin alfa can be used for research of cancer.
-
In Vitro——
-
In VivoAnimal Model:SCLC orthotopic model Dosage:6 mg/kg Administration:s.c., every 4?days Result:Delayed tumor growth and prolonged survival. Animal Model:Male cynomolgus monkeys (PK Assay) Dosage:0.3 or 1 mg/kg Administration:i.v. or s.c.Result:Pharmacokinetic profile of Nemvaleukin alfa.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorInterleukin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2315268-27-8
-
Formula Weight
-
Molecular Formula——
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Human CMV Assemblin ...
Human CMV Assemblin Protease Inhibitor
-
MYCOPHENOLATE SODIUM
Mycophenolic acid (sodium) (Standard) is the analytical standard of Mycophenolic acid (sodium). This product is intended for research and analytical applications. Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects.
-
GPLGIAGQ TFA(109053-...
GPLGIAGQ TFA, is an MMP2-cleaved polypeptide that is used as a stimulus-sensitive connector in both liposomes and micelle nanoceroses for targeted therapy of tumors triggered by MMP2.
