Tidutamab
CAS No. 2148354-90-7
Tidutamab( —— )
Catalog No. M36789 CAS No. 2148354-90-7
Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
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Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1169 | In Stock |
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| 10MG | 1891 | In Stock |
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| 25MG | 2803 | In Stock |
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| 50MG | 3701 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameTidutamab
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NoteResearch use only, not for human use.
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Brief DescriptionTidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors.
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DescriptionTidutamab (XmAb-18087) is a humanized and affinity-optimized bispecific antibody (bsAb) targeting SSTR2 binding domain and T-cell binding domain (CD3). Tidutamab possesses a full Fc domain to maintain long serum half-life.Tidutamab eliminates SSTR+ tumor cells by stimulating redirected T cellmediated cytotoxicity (RTcC).
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In Vitro——
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In VivoAnimal Model:NSG mice Dosage:3 mg/kg Administration:Intraperitoneal injection; single dose Result:lnduced anti-tumor activity in human PBMC-engrafted NSG mice.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2148354-90-7
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Formula Weight
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Cathepsin S substrat...
Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)
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Mepiroxol
3-pyridinemethanol n-oxide, also called Mepiroxol used as antihyperlipidemic.
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Sanggenone H
Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α± and IL-1α2 and inhibited the NF-κB nuclear translocation in LPS-stimulated macrophages.
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