RMC-6236( —— )

Catalog No. M36608 CAS No. 2765081-21-6

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Datasheet

HNMR

HPLC

MSDS

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Product Name

RMC-6236
Note

Research use only, not for human use.
Brief Description

RMC-6236 is a potent RAS(ON)MULTI inhibitor with broad-spectrum inhibitory activity against RAS-GTP and can be used in cancer research.
Description

RAS-IN-2 (Compound A122) is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer.
In Vitro

RAS-IN-2 (Compound A122) (5 days) inhibits cell viability with an IC50 of 1-10 μM against AsPC-1 (K-Ras G12D).
In Vivo

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Synonyms

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Pathway

MAPK/ERK Signaling
Target

Ras
Recptor

Ras
Research Area

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Indication

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CAS Number

2765081-21-6
Formula Weight

811.05
Molecular Formula

C44H58N8O5S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (308.24 mM; Ultrasonic )
SMILES

O=C1OCC(C)(C)CC=2C3=CC(=CC=C3N(C2C=4C=C(C=NC4C(OC)C)N5CCN(C)CC5)CC)C=6N=C(SC6)CC(NC(=O)C7CC7C)C(=O)N8NC1CCC8
Chemical Name

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1. Ethan AHLER, et al. Use of sos1 inhibitors to treat malignancies with shp2 mutations. Patent WO2022060583A1.

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