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CZL55

CAS No. 667408-87-9

CZL55( —— )

Catalog No. M36542 CAS No. 667408-87-9

CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CZL55
  • Note
    Research use only, not for human use.
  • Brief Description
    CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).
  • Description
    CZL55 is a caspase-1 inhibitor with an IC50 value of 24 nM. CZL55 can be used for the research of febrile seizures (FS).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Caspase
  • Recptor
    Caspase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    667408-87-9
  • Formula Weight
    386.4
  • Molecular Formula
    C20H22N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 166.67 mg/mL (431.34 mM; Ultrasonic )
  • SMILES
    N(C(=O)C1=CC(NC(CCCC(O)=O)=O)=CC=C1)C2=C(OC)C=C(OC)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tang Y, et al. Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility. Br J Pharmacol. 2020 Aug;177(15):3519-3534.?
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