CZL55

CAS No. 667408-87-9

CZL55( —— )

Catalog No. M36542 CAS No. 667408-87-9

CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 36 In Stock
5MG 57 In Stock
10MG 93 In Stock
25MG 154 In Stock
50MG 221 In Stock
100MG 332 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CZL55
  • Note
    Research use only, not for human use.
  • Brief Description
    CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).
  • Description
    CZL55 is a caspase-1 inhibitor with an IC50 value of 24 nM. CZL55 can be used for the research of febrile seizures (FS).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Caspase
  • Recptor
    Caspase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    667408-87-9
  • Formula Weight
    386.4
  • Molecular Formula
    C20H22N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 166.67 mg/mL (431.34 mM; Ultrasonic )
  • SMILES
    N(C(=O)C1=CC(NC(CCCC(O)=O)=O)=CC=C1)C2=C(OC)C=C(OC)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tang Y, et al. Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility. Br J Pharmacol. 2020 Aug;177(15):3519-3534.?
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