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BI?3231
CAS No. 2894848-07-6
BI?3231( —— )
Catalog No. M36527 CAS No. 2894848-07-6
BI 3231 is a selective and potent inhibitor of hydroxysteroid 17 -dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 167 | In Stock |
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| 5MG | 150 | In Stock |
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| 10MG | 236 | In Stock |
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| 25MG | 377 | In Stock |
|
| 50MG | 529 | In Stock |
|
| 100MG | 731 | In Stock |
|
| 200MG | 1014 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBI?3231
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NoteResearch use only, not for human use.
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Brief DescriptionBI 3231 is a selective and potent inhibitor of hydroxysteroid 17 -dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.
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DescriptionBI 3231 is a potent and selective hydroxysteroid 17 -dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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RecptorDehydrogenase
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Research Area——
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Indication——
Chemical Information
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CAS Number2894848-07-6
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Formula Weight380.37
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Molecular FormulaC16H14F2N4O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (328.63 mM; Ultrasonic (<60°C)
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SMILESO=C1C(=CN(C(=O)N1CC)CC2=NN=C(S2)C=3C=CC(F)=C(O)C3F)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Thamm S, et, al. Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science. J Med Chem. 2023 Feb 2. ?
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